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Benign prostatic hyperplasia Clinical criteria: The condition must be stable for the prescriber to consider the listed maximum quantity of this medicine suitable for this patient, AND Patient must have lower urinary tract symptoms.
“Pharmacological studies have established that tamsulosin is a selective, potent and competitive α 1- adrenoceptor antagonist and that it has a greater affinity for the α 1A-receptor subtype, predominantly present in the human prostate.”
“T½ (hr) 18.67 (6.99) 15.6 (4.4) 14.6 (7.0)”
“In vitro results suggest that CYP3A4 and also CYP2D6 are involved in metabolism, with possible minor contributions to tamsulosin metabolism by other CYP isozymes.”
Working under the parallel aged-care framework? Aged-care equivalent →
Curated subset. The full adverse-effect list is in the TGA Product Information; click any citation above to open it.